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Sorafenib tosylate




Chinese name:甲苯磺酸索拉非尼

English name:Sorafenib tosylate

Molecular formula/volume:C28H24ClF3N4O6S Exact Mass: 636.11

CAS NO.:475207-59-1

The mechanism of action/target:A kinase inhibitor, can inhibit a variety of tumor cell signal transduction, angiogenesis and apoptosis of intracellular kinase (c – CRAF, mutated BRAF kinase and cell surface (KIT, PLT – 3, RET, RET/PTC, VEGFR – 1, VEGFR – 2, VEGFR – 3, VEGFR – beta)

Indications:Differentiated thyroid cancer, renal cell carcinoma/kidney epithelial renal cell carcinoma, advanced renal cell carcinoma, unresectable liver cancer, liver cancer