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Lapatinib Ditosylate Monohydrate

Time:2016-09-23

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Chinese name:二甲苯磺酸拉帕替尼

English name:Lapatinib Ditosylate Monohydrate

Molecular formula/volume:C43H44ClFN4O11S3 Exact Mass: 942.18

CAS NO.:388082-78-8

The mechanism of action/target:Anthropogenic epidermal growth factor receptor 2 (HER2 / ERBB2) and epidermal growth factor receptor 1 (HER1 / EGFR/ERBB1) tyrosine kinase inhibitors. It combines with phosphorylation of receptor cells structure domain to prevent upon ligand binding receptor phosphorylation (activated)

Indications:Treatment of metastatic or advanced breast cancer and postmenopausal women with hormone receptor positive metastatic breast cancer