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Dronabinol

Time:2016-10-31

Dronabinol

CAS#: 1972-08-3

Description: Dronabinol is a psychoactive compound extracted from the resin of Cannabis sativa. The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound. This cannabinoid (CB) binds with high affinity to both the central CB1 receptor and the peripheral CB2 receptor, working primarily through these receptors, has diverse effects on perception, cognition, pain sensitivity, body temperature, the immune system, fetal development, and more.

Synonym: Dronabinol; Marinol; TETRAHYDROCANNABINOL; Delta9-Tetrahydrocannabinol; Deltanyne; Delta9-THC;Tetrahydrocannabinol, (6a-trans)-Isomer; Tetrahydrocannabinol, (6aR-cis)-Isomer; Tetrahydrocannabinol, (6aS-cis)-Isomer; Tetrahydrocannabinol, Trans Isomer; Tetrahydrocannabinol, Trans-(+-)-Isomer; Tetrahydrocannabinol, Trans-Isomer; THC;

IUPAC/Chemical Name: (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol

Dronabinol, purity > 98%, is not in stock, may be available through custom synthesis. Minimum 1 gram order is requested. Current shipping out time is about 70 days after order is received.

THEORETICAL ANALYSIS

Name: Dronabinol
CAS#: 1972-08-3
Chemical Formula: C21H30O2
Exact Mass: 314.22458
Molecular Weight: 314.46
Elemental Analysis: C, 80.21; H, 9.62; O, 10.18

TECHNICAL DATA

Appearance:
Solid powder
Purity:
>98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition:
Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility:
Soluble in DMSO, not in water
Shelf Life:
>2 years if stored properly
Drug Formulation:
This drug may be formulated in DMSO
Stock Solution Storage:
0 – 4 C for short term (days to weeks), or -20 C for long term (months).

 

REFERENCES

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9: Taylor GH, Schwaitzberg SD. The successful use of dronabinol for failure to
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prevent attenuation of serotonin-induced reflex apneas by dronabinol in
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anorexia nervosa: a randomized controlled trial. Int J Eat Disord. 2014
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18: Zajicek J, Ball S, Wright D, Vickery J, Nunn A, Miller D, Gomez Cano M,
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progression in progressive multiple sclerosis (CUPID): a randomised,
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19: Cooper ZD, Comer SD, Haney M. Comparison of the analgesic effects of
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20: Bedi G, Cooper ZD, Haney M. Subjective, cognitive and cardiovascular
dose-effect profile of nabilone and dronabinol in marijuana smokers. Addict Biol.
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