AZD-4547
CAS#: 1035270-39-3 (1394854-62-6)
Description: AZD4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. FGFR, up-regulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cellular proliferation, differentiation and survival.
Synonym: AZD4547; AZD-4547; AZD 4547.
IUPAC/Chemical Name: N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide
THEORETICAL ANALYSIS
Name: AZD-4547
CAS#: 1035270-39-3 (1394854-62-6)
Chemical Formula: C26H33N5O3
Exact Mass: 463.25834
Molecular Weight: 463.57192
Elemental Analysis: C, 67.36; H, 7.18; N, 15.11; O, 10.35
TECHNICAL DATA
ADDITIONAL INFORMATION
Related CAS#
Sci-Finder listed CAS#1394854-62-6 for AZD-4547
ChemIDplus listed CAS#1035270-39-3 for AZD-4547, see website: https://chem.nlm.nih.gov/chemidplus/rn/1035270-39-3
According to Sci-Finder,
Chemical name for CAS#1394854-62-6:
N-[3-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-5-yl]-4-(3,5-dimethyl-1-piperazinyl)benzamide
Chemical name for CAS#1035270-39-3:
rel-N-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethyl-1-piperazinyl]benzamide
REFERENCES
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